The MSI board is, at best, half the price of the Asus RoG board we've looked at, and for that you do get a rather chunky feature set. What you don't get is the raw performance of the Maximus IV Extreme or the overclocking chops. But for those not necessarily into hardcore OCing, the 4.2GHz you can pick up from the OC Genie alone will suffice.

CPU rendering performance

Cinebench R10 – seconds: quicker is better

MSI P67A-GD65: 38
Asus Maximus IV Extreme: 35

CPU encoding performance – FPS: higher is better

MSI P67A-GD65: 35
Asus Maximus IV Extreme: 35

Overclocking performance

Intel Core i7-2600K – GHz: higher is better

MSI P67A-GD65: 4.2
Asus Maximus IV IV Extreme: 4.6